3 Paths to Get to the Same Place
Managing hypothyroidism can be achieved through different treatment paths, from synthetic T4 medications to natural thyroid options. Understanding these options helps you choose the right approach for your health. For more information, contact us or request an appointment online. We serve patients from Lesslie SC, India Hook SC, Riverview SC, Newport, SC, Catawba SC, Tega Cay SC and surrounding areas.


Choosing Your Path: Comparing 3 Types of Hypothyroidism Management
Finding the right treatment for hypothyroidism is essential for restoring energy, metabolism, quality of life, and more. Treatment options fall into three main categories: synthetic T4, natural desiccated thyroid (DTE), and non-prescription glandular supplements. Understanding the pros and cons is key to making informed decisions.
1. Levothyroxine (Synthroid, Tirosint, Unithroid)
What It Is: This is the most widely prescribed, standard pharmaceutical treatment. Hormone Content: Synthetic T4 only (the inactive storage hormone). How It Works: The body must convert the synthetic T4 into the active T3 hormone for use by the cells.
- Pros: Highly standardized, reliable dosing, and consistent quality.
- Cons: Not effective for the many individuals who struggle with the T4-to-T3 conversion process, leading to persistent hypothyroid symptoms despite “normal” lab results.
2. Desiccated Thyroid Extract (Armour Thyroid, Nature-throid, NP Thyroid)
What It Is: A prescription medication made from the dried thyroid glands of pigs (porcine source). Hormone Content: Natural T4 and Natural T3. DTE provides both the storage and the active hormones in a fixed ratio, which is consistent with the natural hormones found in mammals. How It Works: By supplying both T4 and T3, DTE bypasses the conversion bottleneck, often leading to better symptom resolution for patients who do not respond well to T4-only therapy.
- Pros: Full spectrum of thyroid hormones, bio-identical to human hormones, and often superior for symptom management.
- Cons: Can cause temporary T3-related spikes (like anxiety or racing heart) if the dosage is too high or the release is too quick. Supply and manufacturing have sometimes been inconsistent.
3. Glandular Supplements (Non-Prescription)
What It Is: Over-the-counter supplements, typically from bovine or porcine sources, marketed as thyroid support. Hormone Content: Trace amounts of T4 and T3, plus nutritional co-factors (selenium, iodine, etc.). How It Works: These are nutritional supplements intended to support the thyroid gland with a very small amount of active hormone.
- Pros: Provides foundational nutritional support for thyroid health and are not medications.
- Cons: They lack the standardization and potency to replace prescription therapy.
The Critical Takeaway
For a diagnosed condition, effective management doesn’t alway require a prescription hormone (Levothyroxine or Desiccated Thyroid Extract) under medical supervision. Glandular supplements can have a place in disease management. Consult with your healthcare provider to find the hormonal balance that restores your vitality.





